When you’re pregnant, heartburn isn’t just uncomfortable—it can feel like a daily battle. Safe antacids in pregnancy, medications approved for use during pregnancy to neutralize stomach acid and relieve heartburn without harming the developing baby. Also known as pregnancy-friendly antacids, these are not just any over-the-counter pills—they’re carefully chosen based on decades of safety data and clinical use. Not all antacids are created equal. Some contain ingredients that can cross the placenta, affect fetal development, or interfere with nutrient absorption. Others are gentle, well-studied, and recommended by OB-GYNs and pharmacists alike.
The most trusted options include calcium carbonate, a common antacid ingredient found in Tums and other brands that also provides essential calcium for fetal bone development, and magnesium hydroxide, a mild antacid that’s generally safe in moderation but should be avoided in late pregnancy due to potential effects on uterine contractions. On the flip side, sodium bicarbonate, often found in baking soda remedies, can cause fluid retention and high blood pressure—both risky during pregnancy. Aluminum-based antacids like Maalox are okay in small doses, but long-term use may lead to constipation or reduced phosphate levels, which can impact both you and your baby.
It’s not just about picking the right pill. Timing matters. Taking antacids one to three hours after meals and again at bedtime helps keep acid down when it’s most likely to flare. Avoid lying down right after eating. Skip spicy, fatty, or acidic foods. Eat smaller meals. These simple habits reduce how often you need medication. And if you’re still struggling, talk to your provider about H2 blockers like famotidine—another category of acid reducer that’s considered low-risk in pregnancy and shows up often in trusted clinical guidelines.
What you won’t find on pharmacy shelves are the risky ones: bismuth subsalicylate (Pepto-Bismol), which contains aspirin-like compounds, and any antacid with high levels of magnesium trisilicate. These are not worth the chance. Even natural remedies like apple cider vinegar or baking soda drinks can backfire—they might seem harmless, but they can worsen reflux or cause electrolyte imbalances.
This collection of articles gives you real, no-fluff guidance on what’s safe, what’s not, and how to make smart choices without guesswork. You’ll find comparisons between common brands, insights into how pregnancy changes your digestive system, and practical tips that actually work. Whether you’re in your first trimester and just starting to feel the burn, or in your third and struggling to sleep because of acid reflux, there’s something here for you. No jargon. No scare tactics. Just clear, evidence-backed advice so you can focus on feeling better—and enjoying your pregnancy.